Phospholine Iodide®(echothiophate iodide for ophthalmic solution)

PRODUCT AT-A-GLANCE PRODUCT AT-A-GLANCE
Product: Phospholine Iodide® Phospholine Iodide
Description: 0.125% echothiophate iodide for ophthalmic solution
NDC #: 48102-053-05
Type: Rx
Size: 5 mL
Unit of Sale: Kit containing product, diluent and dropper
Phospholine Iodide

The only commercially available AChE Inhibitor in eyecare

Young fella

Phospholine Iodide® (echothiophate iodide for ophthalmic solution), 0.125% is indicated for the reduction of elevated intraocular pressure (IOP) as well as for the diagnosis and treatment of accommodative esotropia.

The elevated IOP of glaucoma can affect both children and adults. In fact, Phospholine Iodide may be of particular clinical utility in treating aphakic glaucoma, which can occur as a complication of cataract surgery in both young children and adults. By controlling elevated eye pressure in such patients, these important eye drops may also help preserve vital vision.

As a treatment for accommodative esotropia, Phospholine Iodide has proven to be an invaluable therapeutic option to help correct or stabilize the condition, potentially obviating the need for more heroic measures. Or when a young child refuses or has difficulty wearing their corrective glasses, there is still a treatment option that can help.

Now Available from Fera Pharmaceuticals

Phospholine Iodide is sent to your patients directly through our specialty pharmacy partner, Walgreens Specialty Pharmacy. Healthcare providers can simply download and complete a referral form and either fax the completed form to 877-231-8302 or send electronically to Walgreens Specialty Pharmacy – PENNSYLVANIA.

How to prescribe Phospholine Iodide®

What physicians are saying about Phospholine Iodide

It would be great to
have it available
yesterday

It has some
niches that are
pretty unique

This isn’t a rare
disease medicine—
it is just not the most
common disease
medication

Important Safety Information

Contraindications

1. Active uveal inflammation.
2. Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block.
3. Hypersensitivity to the active or inactive ingredients.

Warnings and Precautions

  • Succinylcholine should be administered only with great caution, if at all, prior to or during general anesthesia to patients receiving anticholinesterase medication because of possible respiratory or cardiovascular collapse.
  • Caution should be observed in treating elevated IOP with echothiophate iodide for ophthalmic solution in patients who are at the same time undergoing treatment with systemic anticholinesterase medications, because of possible adverse additive effects.
  • Discontinue the medication if cardiac irregularities occur.
  • Anticholinesterase drugs should be used with caution, if at all, in patients with marked vagotonia, bronchial asthma, spastic gastrointestinal disturbances, peptic ulcer, pronounced bradycardia and hypotension, recent myocardial infarction, epilepsy, parkinsonism, and other disorders that may respond adversely to vagotonic effects.
  • Echothiophate iodide for ophthalmic solution should be used with caution, where there is a prior history of retinal detachment.
  • Temporary discontinuance of medication is necessary if salivation, urinary incontinence, diarrhea, profuse sweating, muscle weakness, or respiratory difficulties occur.
  • Certain types of pesticides, such as organophosphate and carbamate pesticides, may cause more side effects. Wearing a respiratory mask, and frequent washing and clothing change may be recommended around them.

Adverse Reactions

  • Phospholine Iodide may cause eye irritation, including redness, stinging, burning, tearing, eyelid twitching, and blurred eyesight.
  • Iris cysts may form more frequently in children. The cysts usually shrink upon discontinuation of the medication or reducing the frequency of instillation.

For additional information, please click here for Prescribing Information.

You are encouraged to report side effects to the FDA at http://www.FDA.gov/medwatch or 1-800-FDA-1088.

Important Safety Information

Contraindications

1. Active uveal inflammation.
2. Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block.
3. Hypersensitivity to the active or inactive ingredients.

Warnings and Precautions

  • Succinylcholine should be administered only with great caution, if at all, prior to or during general anesthesia to patients receiving anticholinesterase medication because of possible respiratory or cardiovascular collapse.
  • Caution should be observed in treating elevated IOP with echothiophate iodide for ophthalmic solution in patients who are at the same time undergoing treatment with systemic anticholinesterase medications, because of possible adverse additive effects.
  • Discontinue the medication if cardiac irregularities occur.
  • Anticholinesterase drugs should be used with caution, if at all, in patients with marked vagotonia, bronchial asthma, spastic gastrointestinal disturbances, peptic ulcer, pronounced bradycardia and hypotension, recent myocardial infarction, epilepsy, parkinsonism, and other disorders that may respond adversely to vagotonic effects.
  • Echothiophate iodide for ophthalmic solution should be used with caution, where there is a prior history of retinal detachment.
  • Temporary discontinuance of medication is necessary if salivation, urinary incontinence, diarrhea, profuse sweating, muscle weakness, or respiratory difficulties occur.
  • Certain types of pesticides, such as organophosphate and carbamate pesticides, may cause more side effects. Wearing a respiratory mask, and frequent washing and clothing change may be recommended around them.

Adverse Reactions

  • Phospholine Iodide may cause eye irritation, including redness, stinging, burning, tearing, eyelid twitching, and blurred eyesight.
  • Iris cysts may form more frequently in children. The cysts usually shrink upon discontinuation of the medication or reducing the frequency of instillation.

For additional information, please click here for Prescribing Information. You are encouraged to report side effects to the FDA at http://www.FDA.gov/medwatch or 1-800-FDA-1088.

Contraindications

1. Active uveal inflammation.
2. Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block.
3. Hypersensitivity to the active or inactive ingredients.

View Important Safety Information
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