Phospholine Iodide® In Accommodative Esotropia(echothiophate iodide for ophthalmic solution)

The only FDA-approved topical medication for diagnosis and treatment

  • A well-established pediatric safety profile
  • Allows children to avoid glasses without requiring strict cooperation
  • Ideal for children <1 year old, those with special needs, or with poor cooperation
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Important Safety Information

Contraindications

1. Active uveal inflammation.
2. Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block.
3. Hypersensitivity to the active or inactive ingredients.

Warnings and Precautions

  • Succinylcholine should be administered only with great caution, if at all, prior to or during general anesthesia to patients receiving anticholinesterase medication because of possible respiratory or cardiovascular collapse.
  • Caution should be observed in treating elevated IOP with echothiophate iodide for ophthalmic solution in patients who are at the same time undergoing treatment with systemic anticholinesterase medications, because of possible adverse additive effects.
  • Discontinue the medication if cardiac irregularities occur.
  • Anticholinesterase drugs should be used with caution, if at all, in patients with marked vagotonia, bronchial asthma, spastic gastrointestinal disturbances, peptic ulcer, pronounced bradycardia and hypotension, recent myocardial infarction, epilepsy, parkinsonism, and other disorders that may respond adversely to vagotonic effects.
  • Echothiophate iodide for ophthalmic solution should be used with caution, where there is a prior history of retinal detachment.
  • Temporary discontinuance of medication is necessary if salivation, urinary incontinence, diarrhea, profuse sweating, muscle weakness, or respiratory difficulties occur.
  • Certain types of pesticides, such as organophosphate and carbamate pesticides, may cause more side effects. Wearing a respiratory mask, and frequent washing and clothing change may be recommended around them.

Adverse Reactions

  • Phospholine Iodide may cause eye irritation, including redness, stinging, burning, tearing, eyelid twitching, and blurred eyesight.
  • Iris cysts may form more frequently in children. The cysts usually shrink upon discontinuation of the medication or reducing the frequency of instillation.

For additional information, please click here for Prescribing Information.

You are encouraged to report side effects to the FDA at http://www.FDA.gov/medwatch or 1-800-FDA-1088.

Important Safety Information

Contraindications

1. Active uveal inflammation.
2. Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block.
3. Hypersensitivity to the active or inactive ingredients.

Warnings and Precautions

  • Succinylcholine should be administered only with great caution, if at all, prior to or during general anesthesia to patients receiving anticholinesterase medication because of possible respiratory or cardiovascular collapse.
  • Caution should be observed in treating elevated IOP with echothiophate iodide for ophthalmic solution in patients who are at the same time undergoing treatment with systemic anticholinesterase medications, because of possible adverse additive effects.
  • Discontinue the medication if cardiac irregularities occur.
  • Anticholinesterase drugs should be used with caution, if at all, in patients with marked vagotonia, bronchial asthma, spastic gastrointestinal disturbances, peptic ulcer, pronounced bradycardia and hypotension, recent myocardial infarction, epilepsy, parkinsonism, and other disorders that may respond adversely to vagotonic effects.
  • Echothiophate iodide for ophthalmic solution should be used with caution, where there is a prior history of retinal detachment.
  • Temporary discontinuance of medication is necessary if salivation, urinary incontinence, diarrhea, profuse sweating, muscle weakness, or respiratory difficulties occur.
  • Certain types of pesticides, such as organophosphate and carbamate pesticides, may cause more side effects. Wearing a respiratory mask, and frequent washing and clothing change may be recommended around them.

Adverse Reactions

  • Phospholine Iodide may cause eye irritation, including redness, stinging, burning, tearing, eyelid twitching, and blurred eyesight.
  • Iris cysts may form more frequently in children. The cysts usually shrink upon discontinuation of the medication or reducing the frequency of instillation.

For additional information, please click here for Prescribing Information. You are encouraged to report side effects to the FDA at http://www.FDA.gov/medwatch or 1-800-FDA-1088.

Contraindications

1. Active uveal inflammation.
2. Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block.
3. Hypersensitivity to the active or inactive ingredients.

View Important Safety Information
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