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Phospholine Iodide®(echothiophate iodide for ophthalmic solution)

PRODUCT AT-A-GLANCE PRODUCT AT-A-GLANCE
Product: Phospholine Iodide® Phospholine Iodide
Description: 0.125% echothiophate iodide for ophthalmic solution
NDC #: 48102-053-05
Type: Rx
Size: 5 mL
Unit of Sale: Kit containing product, diluent and dropper
Phospholine Iodide
WHOLESALER INFORMATION FOR HEALTHCARE PROVIDERS
For customer service or ordering information,
call 414-434-6604 or fax 414-434-4603.

Product background—and a call to action

Phospholine Iodide® (echothiophate iodide for ophthalmic solution) is indicated for the reduction of elevated intraocular pressure (IOP) as well as for the treatment of accommodative esotropia.

The elevated IOP of glaucoma can affect both children and adults. In fact, Phospholine Iodide may be of particular clinical utility in treating aphakic glaucoma, which can occur as a complication of cataract surgery in both young children and adults. By controlling elevated eye pressure in such patients, these important eye drops may also help preserve vital vision.

As a treatment for accommodative esotropia (the inward turning of the eye) which can cause focusing problems, Phospholine Iodide has proven to be an invaluable therapeutic option to help correct or stabilize the condition, potentially obviating the need for more heroic measures. Or when a young child refuses or has difficulty wearing their corrective glasses, there is still a treatment option that can help.

For years, Phospholine Iodide has been manufactured and marketed by Pfizer. However, for a variety of reasons, Pfizer decided to discontinue the production of this important medication in May 2021, leaving affected patients and families scrambling for a suitable alternative.

Fera Pharmaceuticals has been proud to step in to answer the call. We have completed an agreement with Pfizer to transfer Phospholine Iodide to Fera to ensure its continuous, reliable long-term supply. We were awarded this stewardship based on our expertise in ophthalmic medicines, experience in bringing complex medicines to patients, and our track record navigating the regulatory and FDA approval process. We have worked hard to expedite the return to market of Phospholine Iodide for the small but engaged community of patients, parents and physicians who rely on it.

Pfizer continues to distribute Phospholine Iodide while Fera works to make its own label product available. Please check back here or call customer service for updates on product availability from Fera.

Young fella

Phospholine Iodide® (echothiophate iodide for ophthalmic solution) is indicated for the reduction of elevated intraocular pressure (IOP) as well as for the treatment of accommodative esotropia.

The elevated IOP of glaucoma can affect both children and adults. In fact, Phospholine Iodide may be of particular clinical utility in treating aphakic glaucoma, which can occur as a complication of cataract surgery in both young children and adults. By controlling elevated eye pressure in such patients, these important eye drops may also help preserve vital vision.

Young fella

As a treatment for accommodative esotropia (the inward turning of the eye) which can cause focusing problems, Phospholine Iodide has proven to be an invaluable therapeutic option to help correct or stabilize the condition, potentially obviating the need for more heroic measures. Or when a young child refuses or has difficulty wearing their corrective glasses, there is still a treatment option that can help.

For years, Phospholine Iodide has been manufactured and marketed by Pfizer. However, for a variety of reasons, Pfizer decided to discontinue the production of this important medication in May 2021, leaving affected patients and families scrambling for a suitable alternative.

Fera Pharmaceuticals has been proud to step in to answer the call. We have completed an agreement with Pfizer to transfer Phospholine Iodide to Fera to ensure its continuous, reliable long-term supply. We were awarded this stewardship based on our expertise in ophthalmic medicines, experience in bringing complex medicines to patients, and our track record navigating the regulatory and FDA approval process. We have worked hard to expedite the return to market of Phospholine Iodide for the small but engaged community of patients, parents and physicians who rely on it.

Read full press release

Read Important Safety Information

Young fella

Phospholine Iodide® (echothiophate iodide for ophthalmic solution) is indicated for the reduction of elevated intraocular pressure (IOP) as well as for the treatment of accommodative esotropia.

The elevated IOP of glaucoma can affect both children and adults. In fact, Phospholine Iodide may be of particular clinical utility in treating aphakic glaucoma, which can occur as a complication of cataract surgery in both young children and adults. By controlling elevated eye pressure in such patients, these important eye drops may also help preserve vital vision.

As a treatment for accommodative esotropia (the inward turning of the eye) which can cause focusing problems, Phospholine Iodide has proven to be an invaluable therapeutic option to help correct or stabilize the condition,

Young fella

potentially obviating the need for more heroic measures. Or when a young child refuses or has difficulty wearing their corrective glasses, there is still a treatment option that can help.

For years, Phospholine Iodide has been manufactured and marketed by Pfizer. However, for a variety of reasons, Pfizer decided to discontinue the production of this important medication in May 2021, leaving affected patients and families scrambling for a suitable alternative.

Fera Pharmaceuticals has been proud to step in to answer the call. We have completed an agreement with Pfizer to transfer Phospholine Iodide to Fera to ensure its continuous, reliable long-term supply. We were awarded this stewardship based on our expertise in ophthalmic medicines, experience in bringing complex medicines to patients, and our track record navigating the regulatory and FDA approval process. We have worked hard to expedite the return to market of Phospholine Iodide for the small but engaged community of patients, parents and physicians who rely on it.

Read full press release

Read Important Safety Information

Young fella

What physicians are saying about Phospholine Iodide

It would be great to
have it available
yesterday

It has some
niches that are
pretty unique

This isn’t a rare
disease medicine—
it is just not the most
common disease
medication

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Indication and Usage:

Phospholine Iodide is used for reduction of elevated intraocular pressure and for accommodative esotropia in children.

Important Safety Information:

Contraindications:

Do not use Phospholine Iodide if you have active uveal inflammation or if you are allergic to any ingredient in Phospholine Iodide. Do not use Phospholine Iodide with most cases of angle-closure glaucoma.

Warnings and Precautions:

Wash hands before and after eye drop instillation. Put pressure on the inside corner of the eye with your finger for 1 to 2 minutes following instillation

Use caution and tell your doctor before using Phospholine Iodide if you have: asthma, stomach ulcer, gastrointestinal spasms, slow heartbeat, low blood pressure, recent heart attack, seizures, Parkinson’s disease, or a history of retinal detachment.

Temporarily discontinue the medication and tell your doctor right away if irregular heartbeat, breathing problem, muscle weakness, increased diarrhea, urination, salivation, and/or sweating occurs.

Certain medications, such as succinylcholine and other anticholinesterase medications, may cause more side effects and should only be used with great caution.

Certain types of pesticides, such as organophosphate and carbamate pesticides, may cause more side effects. Wearing a respiratory mask, and frequent washing and clothing change may be recommended around them.

Adverse Reactions:

Phospholine Iodide may cause eye irritation, including redness, stinging, burning, tearing, eyelid twitching, and blurred eye sight.

Iris cysts may form more frequently in children. The cysts usually shrink upon discontinuation of the medication or reducing the frequency of instillation. Talk with your doctor.

For additional information, please click here for Prescribing Information.

You are encouraged to report side effects to the FDA at http://www.FDA.gov/medwatch or 1-800-FDA-1088.

Indication and Usage:

Phospholine Iodide is used for reduction of elevated intraocular pressure and for accommodative esotropia in children.

Important Safety Information:

Contraindications:

Do not use Phospholine Iodide if you have active uveal inflammation or if you are allergic to any ingredient in Phospholine Iodide. Do not use Phospholine Iodide with most cases of angle-closure glaucoma.

Warnings and Precautions:

Wash hands before and after eye drop instillation. Put pressure on the inside corner of the eye with your finger for 1 to 2 minutes following instillation.

Use caution and tell your doctor before using Phospholine Iodide if you have: asthma, stomach ulcer, gastrointestinal spasms, slow heartbeat, low blood pressure, recent heart attack, seizures, Parkinson’s disease, or a history of retinal detachment.

Temporarily discontinue the medication and tell your doctor right away if irregular heartbeat, breathing problem, muscle weakness, increased diarrhea, urination, salivation, and/or sweating occurs.

Certain medications, such as succinylcholine and other anticholinesterase medications, may cause more side effects and should only be used with great caution.

Certain types of pesticides, such as organophosphate and carbamate pesticides, may cause more side effects. Wearing a respiratory mask, and frequent washing and clothing change may be recommended around them.

Adverse Reactions:

Phospholine Iodide may cause eye irritation, including redness, stinging, burning, tearing, eyelid twitching, and blurred eye sight.

Iris cysts may form more frequently in children. The cysts usually shrink upon discontinuation of the medication or reducing the frequency of instillation. Talk with your doctor.

For additional information, please click here for Prescribing Information.

You are encouraged to report side effects to the FDA at http://www.FDA.gov/medwatch or 1-800-FDA-1088.

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Indication and Usage:

Phospholine Iodide is used for reduction of elevated intraocular pressure and for accommodative esotropia in children.

Important Safety Information:

View Important Safety Information